So here are the actresses who starred in two films each alongside Cary Grant.
Jean Arthur:
Only Angels Have Wings (1939) and Talk Of The Town (1942)
Also appeared in the following radio shows:
Only Angels Have Wings (May 28th, 1939)
Talk Of The Town (May 17th, 1943)
Joan Bennett:
Big Brown Eyes (1936) and Wedding Present (1936)
Ingrid Bergman:
Notorious (1946) and Indiscreet (1958)
"She wears no make-up and has big feet and peasant hips, yet women envy her ability to be herself."
- Cary Grant
Nancy Carroll:
Hot Saturday (1932) and Woman Accussed (1933)
Betsy Drake:
Every Girl Should Be Married (1948) and Room For One More (1952)
Also appeared in the following radio show:
Every Girl Should Be Married (June 27th, 1949)
"Betsy was a delightful comedienne, but I don't think Hollywood was ever really her milieu. She wanted to help humanity, to help others help themselves." - Cary Grant
Joan Fontaine:
Gunga Din (1939) and Suspicion (1941)
Sophia Loren:
The Pride and the Passion (1957) and Houseboat (1958)
"I was fascinated with him, with his warmth, affection, intelligence, and his wonderfully dry, mischievous sense of humor." - Sophia Loren
Ginger Rogers:
Once Upon A Honeymoon (1942) and Monkey Business (1952)
Ann Sheridan
Enter Madame (1935: as Clara Lou Sheridan) and I Was a Male War Bride (1949)
Mae West:
She Done Him Wrong (1933) and I'm No Angel (1933)
Loretta Young:
Born To Be Bad (1934) and The Bishop's Wife (1947)